Tablet coating excipients poly acrylates polymer series
(Methacrylic acid co-polymers USP/NF)
Taste and odor masking, light and moisture protection
• Swallowability improvement
• Soluble in gastric fluid up to pH 5.0
• Swellable and permeable above pH 5.0
• Low viscosity
• High pigment binding capacity
• Excellent adhesion
• High effectiveness in thin coatings
POLY ACRYLATE E 100 Granules
POLY ACRYLATE E 12,5 Organic solution
POLY ACRYLATE E PO Powder
POLY ACRYLATE E PO ReadyMix Powder
DELAYED RELEASE:
• Easily combined to achieve a specific dissolution pH
• Highly stable, with rapid dissolution for precise targeting
• Well-defined characteristics to safeguard the gastric mucosa from aggressive actives
• Able to protect the transit of APIs sensitive to gastric fluid
Small Intestine: (ENTERIC COATING)
POLY ACRYLATE L 30 D-55 Aqueous dispersion soluble above pH 5.5
POLY ACRYLATE L 100-55 Powder soluble above pH 5.5
POLY ACRYLATE FL 30 D-55 NEW Aqueous dispersion soluble above pH 5.5
POLY ACRYLATE L 100 Powder soluble above pH 6.0
POLY ACRYLATE L 12,5 Organic solution soluble above pH 6.0
Colonic delivery: (SUSTAINED RELEASE)
POLY ACRYLATE S 100 Powder soluble above pH 7.0
POLY ACRYLATE S 12,5 Organic solution soluble above pH 7.0
POLY ACRYLATE FS 30 D Aqueous dispersion soluble above pH 7.0
POLY ACRYLATE FS 100 Powder soluble above pH 7.0
SUSTAINED RELEASE
• Multiple combination options to control delivery throughout the GI tract
• Solutions for once-per-day dosing, pulsatile release and other custom profiles
• Insoluble with pH-independent permeability
• Flexible options for high or low permeability
POLY ACRYLATE RL PO Powder
POLY ACRYLATE RL 100 Granules
POLY ACRYLATE RL 30 D Aqueous dispersion
POLY ACRYLATE RL 12,5
Organic solution
• Insoluble, high permeability, pH-independent swelling
• Customized release profiles by combining with POLY
ACRYLATE RS at different ratios
POLY ACRYLATE RS PO Powder
POLY ACRYLATE RS 100 Granules
POLY ACRYLATE RS 30 D Aqueous dispersion
POLY ACRYLATE RS 12,5 Organic solution
• Insoluble, low permeability, pH-independent swelling
• Customized release
profiles by combining with POLY ACRYLATE RL at different ratios
POLY ACRYLATE NM 30 D Aqueous dispersion
• Insoluble, low permeability, pH-independent swelling
• Highly flexible, suitable as matrix formers
SOLUBILITY AND
BIOAVAILABILITY ENHANCEMEN
• Polymer, process technology and formulation solutions
• Specialized in solid dispersions, API and silica technologies
• Well-defined processing characteristics for spray drying and hot melt extrusion
• Robust thermoplastic properties
• Broad miscibility with APIs and excipients
• Down-streaming and further processing options
• Predictive systems to select lead carrier excipients and process parameters for trials
Immediate Release
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Colon Targeting
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Delayed Release
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POLY ACRYLATE E 100
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POLY ACRYLATE FS 100
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POLY ACRYLATE L 100
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POLY ACRYLATE E PO
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POLY ACRYLATE S 100
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POLY ACRYLATE L 100-55
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POLY ACRYLATE E 12,5
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POLY ACRYLATE L 12,5
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